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Key Documents

907286

Sigma-Aldrich

H-L-Photo-Proline hydrochloride

≥95%, for peptide synthesis

Synonym(s):

(S)-1,2,5-Triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block

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About This Item

Empirical Formula (Hill Notation):
C5H8ClN3O2
Molecular Weight:
177.59
UNSPSC Code:
12352101
NACRES:
NA.22

product name

H-L-Photo-Proline hydrochloride, ≥95%

assay

≥95%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

storage temp.

−20°C

Application

H-L-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Related product

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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