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907383

Sigma-Aldrich

Fmoc-L-Photo-Lysine

≥95%

Synonym(s):

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C26H30N4O6
CAS Number:
Molecular Weight:
494.54
UNSPSC Code:
12352209

assay

≥95%

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

Application

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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