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Poly(2-methacryloyloxyethyl phosphorylcholine)

Mn 9000

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Synonym(s):
PMPC
Linear Formula:
(C11H22NO6P)n

form

powder or crystals

Quality Level

mol wt

Mn 9000

color

white to beige

SMILES string

O=C(OCCOP(OCC[N+](C)(C)C)([O-])=O)C(C)(C)CC

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This Item
CS0001SAB1402331Z720445
vibrant-m

Z720445

Nalgene® graduated cylinders

form

powder or crystals

form

-

form

buffered aqueous solution

form

-

mol wt

Mn 9000

mol wt

-

mol wt

antigen ~59 kDa

mol wt

-

color

white to beige

color

-

color

-

color

transparent

Application

Poly (2-Methacryloyloxyethyl phosphorylcholine) (PMPC) is a methacrylate based polymer with a zwitterionic phosphorylcholine moiety on the side chain. The phosphorylcholine moiety is very similar to the head group of phospholipids in cell membranes. Due to this unique structure, PMPC showed excellent resistance to nonspecific protein adsorption, cell adhesion, and blood coagulation, as well as cell membrane penetration and underwater lubrication. PMPC has been widely exploited in a diverse range of applications, such as antifouling materials for water treatment, bioengineering, and nanomedicine.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Critical update on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer science
T Goda, et al.
Journal of Applied Polymer Science, 132, 41766-41766 (2015)
Andrew Lewis et al.
Bioconjugate chemistry, 19(11), 2144-2155 (2008-11-01)
The water-soluble, biocompatible polymer poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) was evaluated for protein conjugation. PMPC is a zwitterionic polymer that is able to form a more compact conformation in aqueous solution than poly(ethylene glycol) (PEG). While a terminally functionalized N-hydroxysuccinimide derivative of

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