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926043

Sigma-Aldrich

Carboxymethyl chitosan

Carboxymethylation >/=80%

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Synonym(s):
Carboxymethylchitosan
CAS Number:

Quality Level

color

white to light yellow, light brown

Application

Chitosan offers remarkable biological properties, it has been widely used in drug delivery and tissue engineering applications. Chitosan derivatives have unique properties including biocompatibility, mucoadhesion, non-toxicity, and capability to form gels. Furthermore, they are suitable candidates to manufacture films, tablets, and nanotechnology-based systems which have the possibility for commercial production as well as industrial scale-up. Chemical modification of CS chains using the carboxymethyl moieties will alter the water solubility due to the carboxymethylation degree. The carboxymethyl chitosan derivatives can also interact with cells for applications in cell growth, tissue regeneration, and wound healing.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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1000309185

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An overview of carboxymethyl derivatives of chitosan: Their use as biomaterials and drug delivery systems.
Santos B F, et al.
Materials Science and Engineering, C, 77, 1349-1362 (2017)
In vitro and in vivo studies of a gelatin/carboxymethyl chitosan/LAPONITE? composite scaffold for bone tissue engineering
Tao Li, et al.
Royal Society of Chemistry Advances, 7, 54100?54110-54100?54110 (2017)
Characterization and Application of Carboxymethyl Chitosan-Based Bioink in Cartilage Tissue Engineering.
He Y, et al.
Journal of Nanomaterials (2020)
Utilization of carboxymethyl chitosan in cosmetics.
Jimtaisong A, et al.
International Journal of Cosmetic Science, 36, 12?21-12?21 (2014)
Preparation And Antibacterial Effects Of Carboxymethyl Chitosan-Modified Photo-Responsive Camellia Sapogenin Derivative Cationic Liposomes.
Zhang J, et al.
International journal of nanomedicine, 14, 8611?8626-8611?8626 (2019)

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