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926167

Sigma-Aldrich

Chitosan glycidyl methacrylate

Degree of methacrylation ~20%

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Synonym(s):
Chitosan acrylate, Chitosan methacrylate, Methacrylate grafted chitosan, Methyl methacrylate modified chitosan
Linear Formula:
(C13H21NO7)n (C8H13NO5)m

Quality Level

storage temp.

2-8°C

SMILES string

CO[C@H]1[C@@H](O)[C@@H](N)[C@H](O[C@H]2[C@@H](O)[C@@H](NC(C)=O)[C@H](C)O[C@@H]2CO)O[C@@H]1COCC(O)COC(C(C)=C)=O

Application

The unique physicochemical properties offer chitosan great potential in a range of biomedical applications such as tissue engineering, drug delivery vehicles, and enzyme immobilization for biosensing. Methacrylate functionalized chitosan is thermo/photo cross-linkable and used as a precursor for the fabrication of hydrogels in a wide range of biomedical applications including tissue engineering, 3D bioprinting, and drug and gene delivery. Chitosan-based material also has mucoadhesive properties and hence widely used in transmucosal therapeutics delivery.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Panita Maturavongsadit et al.
ACS applied bio materials, 4(3), 2342-2353 (2022-01-12)
3D bioprinting has recently emerged as a very useful tool in tissue engineering and regenerative medicine. However, developing suitable bioinks to fabricate specific tissue constructs remains a challenging task. Herein, we report on a nanocellulose/chitosan-based bioink, which is compatible with
Oluwadamilola M Kolawole et al.
International journal of pharmaceutics, 550(1-2), 123-129 (2018-08-22)
Chitosan is a cationic polysaccharide that exhibits mucoadhesive properties which allow it to adhere to mucosal tissues. In this work, we explored chemical modification of chitosan through its reaction with methacrylic anhydride to synthesise methacrylated derivative with the aim to
Shefali Jaiswal et al.
Carbohydrate polymers, 211, 109-117 (2019-03-03)
A methyl methacrylate (MMA) modified chitosan (CS) conjugate (CSMMA) has been synthesized by a green method via Michael addition reaction between CS and MMA in ethanol. The synthesized conjugate was characterized by FT-IR, 1H NMR, X-ray diffraction spectrometry and SEM
Mina Rajabi et al.
Carbohydrate polymers, 260, 117768-117768 (2021-03-14)
Tissue engineering and regenerative medicine have entered a new stage of development by the recent progress in biology, material sciences, and particularly an emerging additive manufacturing technique, three-dimensional (3D) printing. 3D printing is an advanced biofabrication technique which can generate
Md Minhajul Islam et al.
Bioactive materials, 5(1), 164-183 (2020-02-23)
In recent years, there have been increasingly rapid advances of using bioactive materials in tissue engineering applications. Bioactive materials constitute many different structures based upon ceramic, metallic or polymeric materials, and can elicit specific tissue responses. However, most of them

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