G6104
Glycinamide hydrochloride
98%
Synonym(s):
2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride
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All Photos(3)
About This Item
Linear Formula:
NH2CH2CONH2 · HCl
CAS Number:
Molecular Weight:
110.54
Beilstein/REAXYS Number:
3554199
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
mp
204 °C (dec.) (lit.)
SMILES string
Cl.NCC(N)=O
InChI
1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
Inchi Key
WKNMKGVLOWGGOU-UHFFFAOYSA-N
Application
Buffer useful in the physiological pH range.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lihu Yang et al.
Bioorganic & medicinal chemistry letters, 16(14), 3735-3739 (2006-05-16)
Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity (IC50=30 and 39 nM) toward human monocytes and CHO cell expressing human CCR2b, respectively. Functionally, it
Carolina García-Martínez et al.
The journal of pain : official journal of the American Pain Society, 7(10), 735-746 (2006-10-05)
Vanilloid receptor subunit 1 (TRPV1) is an integrator of physical and chemical stimuli in the peripheral nervous system. This receptor plays a key role in the pathophysiology of inflammatory pain. Thus, the identification of receptor antagonists with analgesic and anti-inflammatory
Hong Zhao et al.
Bioconjugate chemistry, 17(2), 341-351 (2006-03-16)
The utility of PEGylation for improving therapeutic protein pharmacology would be substantially expanded if the authentic protein drugs could be regenerated in vivo. Diminution of kinetic constants of both enzymes and protein ligands are commonly encountered following permanent bioconjugation with
Irene M Lagoja et al.
Chemistry & biodiversity, 2(7), 923-927 (2006-12-29)
A possible reaction mechanism for the dehydration of glycinamide (3) and N,N'-diformylurea (4) yielding hypoxanthine (2) has been investigated. Furthermore, a potential prebiotic route converting hypoxanthine (2) into adenine (1) via phosphate activation followed by substitution reaction with NH3 was
Yong Sun et al.
The journal of physical chemistry. B, 109(12), 5919-5926 (2006-07-21)
For the purpose of investigating the tautomerism from glycinamide (G) to glycinamidic acid (G*) induced by proton transfer, we carried out a study of structural interconversion of the two tautomers and the relative stabilizing influences of water during the tautomerization
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