P50803

Propargyl alcohol

99%

• Synonym(s): 2-Propyn-1-ol
• Linear Formula: HC≡CCH₂OH
• CAS Number: 107-19-7
• Molecular Weight: 56.06
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24898591
• EC Number: 203-471-2
• Beilstein/REAXYS Number: 506003
• MDL number: MFCD00002912
• Assay: 99%

Properties

• vapor density: 1.93 (vs air)
• Quality Level: 100
• vapor pressure: 11.6 mmHg ( 20 °C)
• assay: 99%
• refractive index: n20/D 1.432 (lit.)
• bp: 114-115 °C (lit.)
• mp: −53 °C (lit.)
• density: 0.963 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: OCC#C
• InChI: 1S/C3H4O/c1-2-3-4/h1,4H,3H2
• InChI key: TVDSBUOJIPERQY-UHFFFAOYSA-N

Description

Application

Propargyl alcohol has been used as a key starting material in the [4+2] cycloisomerization mediated synthesis of various phthalide derivatives.
It can also be used to synthesize:

• A variety of regioselective furan-3-carboxamides by reacting with 3-oxo amides using Ag₂CO₃ as a promoter.
• β-oxopropyl esters by reacting with carboxylic acids in the presence of (arene) (phosphine)ruthenium(II) complex as a catalyst.

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H226,H301 + H331,H310,H314,H373,H411
• pcodes: P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT RE 2
• target_organs: Liver,Kidney
• Storage Class: 3 - Flammable liquids
• wgk: WGK 3
• flash_point_f: 91.4 °F - closed cup
• flash_point_c: 33 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter