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N-005

Supelco

Norcodeine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Empirical Formula (Hill Notation):
C17H19NO3
CAS Number:
Molecular Weight:
285.34
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

COc1ccc2C[C@H]3NCC[C@@]45[C@@H](Oc1c24)[C@@H](O)C=C[C@@H]35

InChI

1S/C17H19NO3/c1-20-13-5-2-9-8-11-10-3-4-12(19)16-17(10,6-7-18-11)14(9)15(13)21-16/h2-5,10-12,16,18-19H,6-8H2,1H3/t10-,11+,12-,16-,17-/m0/s1

InChI key

HKOIXWVRNLGFOR-KOFBORESSA-N

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Norcodeine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Normeperidine solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-089

Normeperidine solution

format

single component solution

format

single component solution

format

single component solution

format

single component solution

form

liquid

form

liquid

form

liquid

form

liquid

grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Cerilliant®

manufacturer/tradename

Cerilliant®

manufacturer/tradename

Cerilliant®

manufacturer/tradename

Cerilliant®

General description

Norcodeine is a primary urinary metabolite of codeine. Codeine is an opiate used for its analgesic, antitussive, and sedative properties and is the second-most predominant alkaloid in opium. This certified Snap-N-Spike® Solution is applicable for use in LC/MS or GC/MS applications from urine drug testing and pain prescription monitoring to clinical toxicology and forensic analysis.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


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Z R Chen et al.
Journal of chromatography, 491(2), 367-378 (1989-07-21)
A novel high-performance liquid chromatographic method for the determination of codeine, norcodeine and morphine in plasma and urine has been developed. The compounds were separated on a cyano column (15 cm x 4.6 mm, 5 microns particle size) using a
J O Svensson et al.
Journal of chromatography. B, Biomedical applications, 674(1), 49-55 (1995-12-01)
A reversed-phase ion-pair high-performance liquid chromatographic method for the simultaneous determination of codeine and seven metabolites is described. The samples are purified by reversed-phase solid-phase extraction. Codeine, norcodeine, codeine-6-glucuronide, norcodeine-6-glucuronide and morphine-3-glucuronide are measured with UV detection. Detection limits are
O Mortimer et al.
Clinical pharmacology and therapeutics, 47(1), 27-35 (1990-01-01)
We studied the oxidation capacity in liver biopsies of a series of extensive metabolizers (n = 10) and poor metabolizers (n = 2) as identified by in vivo phenotyping with dextromethorphan. Codeine and dextromethorphan were used as probe drugs in
Q Y Yue et al.
Pharmacogenetics, 4(4), 193-198 (1994-08-01)
The inducibility of codeine metabolism by carbamazepine (CBZ) and cigarette smoking has been investigated. A single oral dose of 25 mg of codeine was given to seven epileptic patients before and after 3 weeks' regular CBZ treatment (400-600 mg per
[Morphinan alkaloids present in mammal].
Y M Ning et al.
Sheng li ke xue jin zhan [Progress in physiology], 21(4), 329-332 (1990-10-01)

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