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218735

Sigma-Aldrich

Caspase Inhibitor II

The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):

Caspase Inhibitor II, Ac-VAD-CHO

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About This Item

Empirical Formula (Hill Notation):
C14H23N3O6
CAS Number:
Molecular Weight:
329.35
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

DMSO: 150 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C14H23N3O6/c1-7(2)12(16-9(4)19)14(23)15-8(3)13(22)17-10(6-18)5-11(20)21/h6-8,10,12H,5H2,1-4H3,(H,15,23)(H,16,19)(H,17,22)(H,20,21)/t8-,10-,12-/m0/s1

InChI key

BGFYQRSQECIBIB-PEXQALLHSA-N

General description

A potent and reversible inhibitor of caspases.
A potent and reversible pan-caspase inhibitor.

Biochem/physiol Actions

Cell permeable: no
Primary Target
pan-caspase
Product does not compete with ATP.
Reversible: yes

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Val-Ala-Asp-CHO

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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