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218739

Sigma-Aldrich

Caspase-1 Substrate X, Fluorogenic

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

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Synonym(s):
Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
Empirical Formula (Hill Notation):
C38H40N8O11
CAS Number:
Molecular Weight:
784.77

Quality Level

assay

≥95% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

solubility

DMSO: 5 mg/mL

fluorescence

λex 365–380 nm
λem 430–460 nm

shipped in

ambient

storage temp.

−20°C

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688225218765264151
Sigma-Aldrich

218739

Caspase-1 Substrate X, Fluorogenic

Sigma-Aldrich

218765

Caspase-9 Substrate I, Fluorogenic

form

lyophilized

form

solid

form

solid

form

lyophilized solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 5 mg/mL

solubility

DMSO: 5 mg/mL

solubility

DMSO: 5 mg/mL

solubility

DMSO: 5 mg/mL

General description

A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).
A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Trp-Glu-His-Asp-AMC

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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