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Dithioerythritol

A protective agent for SH groups.

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Synonym(s):
Dithioerythritol, Cleland’s Other Reagent, DTE
Empirical Formula (Hill Notation):
C4H10O2S2
CAS Number:
Molecular Weight:
154.25
MDL number:

Quality Level

assay

≥98% (titration)

form

solid

reaction suitability

reagent type: reductant

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

<1% disulfides (UV)

color

white

pH

4.5-6.5 (25 °C, 15.4 g/L)

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+

InChI key

VHJLVAABSRFDPM-ZXZARUISSA-N

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Dithioerythritol A protective agent for SH groups.

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Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

impurities

<1% disulfides (UV)

impurities

Insoluble matter, passes filter test, ≤0.0005% Phosphorus (P)

impurities

-

impurities

-

solubility

water: 50 mg/mL

solubility

H2O: 0.1 M, clear, colorless

solubility

-

solubility

H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow

pH

4.5-6.5 (25 °C, 15.4 g/L)

pH

4.5-6.5 (0.1 M in H2O)

pH

4.5-6.5 (25 °C, 15.4 g/L)

pH

-

form

solid

form

powder

form

powder

form

powder

General description

A protective agent for SH groups.
Water-soluble, cell-permeable protective reagent for sulfhydryl groups. Maintains monothiols in the reduced state and reduces disulfides quantitatively. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro.

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 2 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3


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