250255-M
Cytochalasin D
from Zygosporium mansonii, ≥98% (TLC), solid, fungal toxin, Calbiochem®
Synonym(s):
Cytochalasin D, Zygosporium mansonii
About This Item
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Cytochalasin D, Zygosporium mansonii, Cytochalasin D, Zygosporium mansonii, CAS 22144-77-0, is a fungal toxin that is about 10-fold more potent than cytochalasin B in inhibiting actin filament function. Blocks cytoplasmic division.
Quality Level
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white
solubility
DMSO: 2 mg/mL
chloroform: 2 mg/mL
storage temp.
−20°C
InChI
1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
InChI key
SDZRWUKZFQQKKV-JHADDHBZSA-N
General description
Biochem/physiol Actions
Actin filament function
Warning
Reconstitution
Other Notes
Blankson, H., et al. 1995. Exp. Cell Res.218, 522.
Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun.209, 1102.
Verschueren, H., et al. 1995. Eur. J. Cell Biol.66, 335.
Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
Betina, V., and Micekova, D. 1972. Chem. Abstr.77, 160508q.
Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.
Legal Information
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
wgk_germany
WGK 3
Certificates of Analysis (COA)
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