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Sigma-Aldrich

DNP-Hemocyanin Conjugate, Keyhole Limpet

DNP-Hemocyanin Conjugate, Keyhole Limpet, is useful for production of antibodies specific for DNP and hemocyanin. Contains ≥400 DNP-groups per molecule of protein.

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Synonym(s):
DNP-KLH
UNSPSC Code:
12352202
NACRES:
NA.25

Quality Level

form

solid (fluffy)

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

yellow

shipped in

ambient

storage temp.

2-8°C

General description

DNP conjugate useful for production of antibodies specific for DNP and hemocyanin. Contains ≥400 DNP-groups per molecule of protein.
One of the primary aspects of the immune response is the interaction of antigens with lymphocytes to induce the formation of antibodies, that in turn makes the antigen harmless. Much of our current understanding of the antibody response to antigens has been derived by using the antibody-hapten model. One known model uses the dinitrophenyl (DNP) group. Immunization of many mammalian species with DNP-protein conjugates results in production of antibodies specific for DNP and the amino acid side chains to which it is attached. DNP conjugate useful for production of antibodies specific for DNP and hemocyanin. Contains 400 DNP-groups per molecule.

Warning

Toxicity: Standard Handling (A)

Preparation Note

May require gentle heating and stirring for 1-2 h. Do not use phosphate-buffered saline to dissolve the product.

Other Notes

Little, J.R. and Eiser, H.N. 1967. Methods Immunol. Immunochem.1, 128.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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