8.52062
Fmoc-Tic-OH
Novabiochem®
Synonym(s):
Fmoc-Tic-OH, N-1-Fmoc-L-1,2,3,4,-tetrahydro-isoquinoline-3-carboxylic acid
About This Item
Recommended Products
Quality Level
product line
Novabiochem®
assay
≥97.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
15-25°C
InChI
1S/C25H21NO4/c27-24(28)23-13-16-7-1-2-8-17(16)14-26(23)25(29)30-15-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h1-12,22-23H,13-15H2,(H,27,28)/p-1/t23-/m0/s1
InChI key
LIRBCUNCXDZOOU-QHCPKHFHSA-M
Related Categories
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] M. Vincent, et al. (1982) Tetrahedron Lett., 16, 1677.
[2] P. L. Julian, et al. (1984) J. Am. Chem. Soc., 79, 180.
[3] W. A. Kazmierski, et al. (1988) Tetrahedron Lett., 44, 697.
Linkage
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 1.00 %
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Legal Information
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
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