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AB1128

Sigma-Aldrich

Anti-Respiratory Syncytial Virus Antibody

Chemicon®, from goat

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Synonym(s):
RSV
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

shipped in

wet ice

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antibody form

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antibody form

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antibody form

ascites fluid

antibody form

purified immunoglobulin

biological source

goat

biological source

mouse

biological source

mouse

biological source

mouse

clone

polyclonal

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133-1H, monoclonal

clone

130-8F, monoclonal

clone

monoclonal

shipped in

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shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

technique(s)

ELISA: suitable, immunohistochemistry: suitable (paraffin), immunofluorescence: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable (paraffin)

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Specificity

Recognizes RSV, all antigens. Does not react with Para 1-3, Influenza A & B and Adenovirus by IFA. Non reactive with HEp-2 cells and WI-38 cells.

Immunogen

Human RSV isolate

Application

Anti-Respiratory Syncytial Virus Antibody is an antibody against Respiratory Syncytial Virus for use in ELISA, IF, IH(P).
Indirect immunofluorescence: 1:480.

Reactive in paraffin embedded sections (see matsuse, et al 2000).

ELISA: 1:10,000

Fusion inhibition (1:256)

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin in PBS (0.01 M, pH 7.2) with 0.1% sodium azide.

Storage and Stability

Maintain -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells.
San-Juan-Vergara, H; Peeples, ME; Lockey, RF; Mohapatra, SS
Journal of virology null
Recombinant influenza virus carrying the respiratory syncytial virus (RSV) F85-93 CTL epitope reduces RSV replication in mice.
De Baets, S; Schepens, B; Sedeyn, K; Schotsaert, M; Roose, K; Bogaert, P; Fiers, W; Saelens, X
Journal of virology null
Respiratory syncytial virus glycoproteins uptake occurs through clathrin-mediated endocytosis in a human epithelial cell line.
Abel Gutierrez-Ortega,Carla Sanchez-Hernandez,Beatriz Gomez-Garcia
Virology Journal null
Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation.
Webster Marketon, JI; Corry, J
FEBS Open Bio null
Weidong Zhang et al.
Nature medicine, 11(1), 56-62 (2004-12-28)
Respiratory syncytial virus (RSV) infection is one of the major causes of respiratory tract infection for which no vaccine or antiviral treatment is available. The RSV NS1 protein seems to antagonize the host interferon (IFN) response; however, its mechanism is

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