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AB9040

Sigma-Aldrich

Anti-Nerve Growth Factor Antibody, pro

serum, Chemicon®

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Synonym(s):
proNGF
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NTF3(4908)

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This Item
AB5583AB1532SPAB1532P
Sigma-Aldrich

AB1532SP

Anti-Neurotrophin 3 Antibody

Anti-Neurotrophin 3 Antibody Chemicon®, from rabbit

AB1532P

Anti-Neurotrophin 3 Antibody

antibody form

serum

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity purified immunoglobulin

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

technique(s)

immunohistochemistry: suitable, western blot: suitable, immunoprecipitation (IP): suitable

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

immunohistochemistry: suitable, western blot: suitable

species reactivity

rat, human, mouse

species reactivity

rat

species reactivity

rat, chicken, human

species reactivity

rat, human, chicken

Gene Information

human ... NTF3(4908)

Gene Information

human ... NTF3(4908)

Gene Information

human ... NTF3(4908)

Gene Information

human ... NTF3(4908)

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Specificity

Reacts with proNGF.

Immunogen

Recombinant protein from mouse proNGF.

Application

Anti-Nerve Growth Factor Antibody, pro is an antibody against Nerve Growth Factor for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Western blot: 1:250-1:500. Reacts with bands of 30 kD and 32 kD.

Immunohistochemistry: 1:250 on frozen sections.

Immunocytochemistry

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Physical form

Rabbit serum. Liquid.

Storage and Stability

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Sam Faulkner et al.
Oncotarget, 7(19), 28488-28497 (2016-04-14)
The precursor for nerve growth factor (proNGF) is expressed in some cancers but its clinicopathological significance is unclear. The present study aimed to define the clinicopathological significance of proNGF in thyroid cancer. ProNGF expression was analysed by immunohistochemistry in two
Bernadette Rogez et al.
Veterinary pathology, 57(4), 507-519 (2020-05-01)
Accumulating data highlight the role of neurotrophins and their receptors in human breast cancer. This family includes nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), both synthetized as proneurotrophins (proNGF and proBDNF). (pro)NGF and (pro)BDNF initiate their biological effects
Christopher W Rowe et al.
Scientific reports, 10(1), 1539-1539 (2020-02-01)
Nerves are emerging regulators of cancer progression and in several malignancies innervation of the tumour microenvironment is associated with tumour aggressiveness. However, the innervation of thyroid cancer is unclear. Here, we investigated the presence of nerves in thyroid cancers and
Fangfang Gao et al.
Scientific reports, 8(1), 8135-8135 (2018-05-29)
The neurotrophic tyrosine kinase receptor TrkA (NTRK1) and its ligand nerve growth factor (NGF) are emerging promoters of tumor progression. In lung cancer, drugs targeting TrkA are in clinical trials, but the clinicopathological significance of TrkA and NGF, as well
Francesca Malerba et al.
Frontiers in molecular neuroscience, 9, 63-63 (2016-08-19)
The homeostasis between mature neurotrophin NGF and its precursor proNGF is thought to be crucial in physiology and in pathological states. Therefore, the measurement of the relative amounts of NGF and proNGF could serve as a footprint for the identification

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