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CBL1512F

Sigma-Aldrich

Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated

clone OX-42, Chemicon®, from mouse

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Synonym(s):
CD11b
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

FITC conjugate

antibody product type

primary antibodies

clone

OX-42, monoclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

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This Item
CBL1512ZCBL1512F2648
conjugate

FITC conjugate

conjugate

-

conjugate

-

conjugate

FITC conjugate

clone

OX-42, monoclonal

clone

OX-42, monoclonal

clone

OX-42, monoclonal

clone

ICRF44, monoclonal

species reactivity

rat

species reactivity

rat

species reactivity

rat

species reactivity

human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

-

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable (paraffin), immunoprecipitation (IP): suitable

technique(s)

flow cytometry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable

technique(s)

flow cytometry: 10 μL using 1 × 106 cells

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Specificity

This antibody recognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95 KDa. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
FUSION PARTNER: NSO myeloma cell line.

Application

Flow cytometry

Immunohistochemical studies of rat fresh frozen tissue sections following either periodate-lysine-paraformaldehyde (PLP) fixation, or acetone. Works on very lightly PFA fixed, frozen tissues. (perfusion only 4% PFA 10-15′ no post-fix).

Optimal working dilutions must be determined by the end user.
This Anti-Integrin αM CD11b Antibody, clone OX-42, FITC conjugated is validated for use in FC, IH for the detection of Integrin αM [CD11b].

Linkage

Replaces: MAB1404F

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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