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MAB344

Sigma-Aldrich

Anti-O1 Antibody, clone 59

clone 59, Chemicon®, from mouse

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eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

saturated ammonium sulfate (SAS) precipitated

clone

59, monoclonal

species reactivity

chicken, rat, mouse, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgM

shipped in

wet ice

target post-translational modification

unmodified

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This Item
AB3768AB5714MAB4381
vibrant-m

MAB344

Anti-O1 Antibody, clone 59

vibrant-m

AB3768

Anti-Rad54L Antibody

vibrant-m

AB5714

Anti-Hey 1/HRT1 Antibody

clone

59, monoclonal

clone

polyclonal

clone

polyclonal

clone

TRA-1-81, monoclonal

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

mouse

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

saturated ammonium sulfate (SAS) precipitated

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

isotype

IgM

isotype

-

isotype

-

isotype

IgM

Specificity

Recognizes Oligodendrocyte marker O1. Also reacts with certain galactolipids in sperm (see Additional Information library for list).

Immunogen

White matter of corpus callosum from rat brain.

Application

Anti-O1 Antibody, clone 59 is an antibody against O1 for use in IH.
Immunohistochemistry: 10-20 μg/mL on unfixed, shock frozen tissue.

Note: 01 is a lipid which is released from the membrane by alcohol.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Physical form

Format: Purified
Liquid. Buffer = 0.05 M Potassium Phosphate, 0.3 M NaCl, pH 8.0 with 0.05% sodium azide.

Storage and Stability

Maintain lyophilized material at +2–8°C for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Oligodendrocyte culture, Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Jong-Wan Kim et al.
Folia neuropathologica, 57(1), 24-35 (2019-05-01)
This study was performed to determine whether the disturbed maturation of oligodendrocyte (OL) progenitors might be related to lipopolysaccharide (LPS)-induced hypomyelination. We created organotypic cultures of forebrain slices from neonatal rats and explored the morphological changes of glial cells expressing
Generation of functional neurons and glia from multipotent adult mouse germ-line stem cells.
Streckfuss-Bomeke, Katrin, et al.
Stem Cell Research, 2, 139-154 (2009)
Immuno-electron-microscopic identification of O-antigen-bearing oligodendroglial cells in vitro
Berg, G and Schachner, M
Cell and Tissue Research, 219, 313-325 (1981)
Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells.
Karen L Lankford,Masanori Sasaki,Christine Radtke,Jeffery D Kocsis
Glia null
Chao Jiang et al.
Molecular neurobiology (2016-01-10)
Studies have shown that progesterone enhances functional recovery after ischemic stroke, but the underlying mechanisms are not completely understood. Therefore, we investigated the effect of progesterone on vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), and neurogenesis in a

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