MAB3706

Anti-CD4 Antibody, intracellular, clone 024-10D6.B3

clone 024-10D6.B3, Chemicon^®, from mouse

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• clone: 024-10D6.B3, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable; electrophoretic mobility shift assay: suitable; immunocytochemistry: suitable
• isotype: IgG1
• NCBI accession no.: NM_000616.3
• UniProt accession no.: P01730
• shipped in: wet ice
• target post-translational modification: unmodified

Description

Specificity

Recognizes the cytoplasmic tail of CD4. Many functions have been assigned to this tail, including anti-viral regulation (down/up regulation of CD4), T-cell maturation, activation and differentiation, and Lck signal transduction, among others. This antibody is useful as a control for studies involving targeting of intracellular protein domains of T cells.

Immunogen

Synthetic peptide corresponding to amino acids 439-458 of the cytoplasmic tail of human CD4.

Application

Detect CD4 using this Anti-CD4 Antibody, intracellular, clone 024-10D6.B3 validated for use in ELISA, EMSA, FUNC & IC.

Immunocytochemistry

ELISA

Stimulation/Inhibition of biological activity

Electrophoretic mobility shift analysis

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified

Purified immunoglobulin. Liquid in 0.02 M phosphate buffer, 0.25M NaCl, with 0.1% sodium azide.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable