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Key Documents

MAB8691

Sigma-Aldrich

Anti-Hepatitis C Virus Antibody, helicase domain NS3

Chemicon®, from mouse

Synonym(s):

HCV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

shipped in

wet ice

Specificity

Specific to HCV NS3, helicase domain.

Immunogen

Recombinant protein to NS3

Application

Anti-Hepatitis C Virus Antibody, helicase domain NS3 detects level of Hepatitis C Virus & has been published & validated for use in ELISA, IF, WB, IH(P).
ELISA

Immunohistochemistry (Parrafin embedded)

Immunofluorescence

Immunoblot

Final dilutions must be determined by end user
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Liquid in PBS, pH 7.4 containing no preservatives

Storage and Stability

Store at -20°C in undiluted aliquots for up to 6 months from date of receipt; avoid repeated freeze-thaw cycles; short-term storage (1 week) can be at 2-8°C. Use with sterile tips to prevent contamination.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jun Zhang et al.
Molecular medicine reports, 12(4), 5109-5115 (2015-07-08)
Chronic hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) worldwide. The HCV non‑structural protein 3 (NS3) protein is considered to affect normal cellular functions and to be involved in HCV carcinogenesis. The expression of microRNA
Adi Ariffianto et al.
The Kobe journal of medical sciences, 69(3), E86-E95 (2023-09-04)
We previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK
Shao-Ru Chen et al.
Molecules (Basel, Switzerland), 21(10) (2016-10-19)
Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone
Rheza Gandi Bawono et al.
The Kobe journal of medical sciences, 67(2), E38-E47 (2021-11-20)
We previously reported that hepatitis C virus (HCV) NS5A (1b, Con1) protein accepts covalent ISG15 conjugation at specific lysine (Lys) residues (K44, K68, K166, K215 and K308), exhibiting proviral effects on HCV RNA replication. Here we investigated a role of
Ciniso Sylvester Shabangu et al.
Biomedicines, 9(10) (2021-10-24)
A large amount of epidemiological evidence indicates that persistent HCV infection is the main risk factor for HCC. We aimed to study the effects of persistent HCV infection on the interaction of the virus and host cell to identify cancer

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