MABC991
Anti-PD-L1 Antibody, clone 10F.9G2
clone 10F.9G2, from rat
Synonym(s):
PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274
About This Item
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biological source
rat
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
10F.9G2, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
inhibition assay: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
General description
Specificity
Immunogen
Application
Induces Function Analysis: Blockade with a representative lot of anti-PD-L1 combined with IL-2 enhanced antiviral CD8 T cell responses during chronic LCMV infection (West, E.E., et. al. (2013). J Clin Invest. 123(6):2604-15).
Inhibition Analysis: A representative lot blocked the action of PD-L1 (Grabie, N., et. al. (2007). Circulation. 116(18):2062-71;West, E.E., et. al. (2013). J Clin Invest. 123(6):2604-15;El Annan, J., et. al. (2010). Invest Ophthalmol Vis Sci. 51(7):3418-23).
Quality
Flow Cytometry Analysis: 1 µg/mL of this antibody detected PD-L1 in one million EL4 cells.
Target description
Linkage
Physical form
Other Notes
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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