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MATRESIQUIM0D

Millipore

Resiquimod Non-Endotoxin Pyrogen (NEP) Control

for use with PyroMAT®

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Synonym(s):
Imidazoquinolinon

Agency

EP
JP 4.06
USP

Quality Level

400

form

lyophilized

application(s)

pharmaceutical
pyrogen testing

compatibility

for use with PyroMAT®

shipped in

ambient

storage temp.

−20°C

suitability

pyrogenic bacteria

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MATPAM3CSK41.44161MATHKSA
Resiquimod Non-Endotoxin Pyrogen (NEP) Control for use with PyroMAT®

Millipore

MATRESIQUIM0D

Resiquimod Non-Endotoxin Pyrogen (NEP) Control

PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control for use with PyroMAT®

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MATPAM3CSK4

PAM3CSK4 Non-Endotoxin Pyrogen (NEP) Control

Reference Standard Endotoxin EDQM endotoxin standard for Monocyte Activation Test

Millipore

1.44161

Reference Standard Endotoxin

NEP Control HKSA- PyroMAT® System MAT Non-endotoxin pyrogen control of heat killed Staphyloccus aureus for use in monocyte activation test

Millipore

MATHKSA

NEP Control HKSA- PyroMAT® System MAT

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

compatibility

for use with PyroMAT®

compatibility

for use with PyroMAT®

compatibility

configured for PyroDetect System, configured for PyroMAT® System

compatibility

configured for PyroDetect System, configured for PyroMAT® System

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

suitability

pyrogenic bacteria

suitability

pyrogenic bacteria

suitability

pyrogenic bacteria

suitability

pyrogenic bacteria

Quality Level

400

Quality Level

400

Quality Level

200

Quality Level

400

General description

Resiquimod is a non-endotoxin pyrogen which will serve as a positive control during pyrogen testing with PyroMAT® system.Non- Endotoxin Pyrogen (NEP) Control Resiquimod is an imidazoquinolinone compound possessing a potent anti-viral activity, supplied in a lyophilized form. It is designed to mimic the NEPs of viral origin. Resiquimod Non- Endotoxin Pyrogen (NEP) Control activates TLR7/TLR8 receptor of monocytes and is used as a positive control for PyroMAT® system. The response to pyrogenic substances is determined by measuring the Interleukin-6 (IL-6) produced by the monocytes using ELISA microplate.

Application

Resiquimod Non- Endotoxin Pyrogen (NEP) Control can be used as a positive control with the PyroMAT® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

Legal Information

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

control

Product No.
Description
Pricing

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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