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PYR0MATKIT

Millipore

PyroMAT® kit

Reagents and Interleukin-6 ELISA kit for Monocyte Activation Test (MAT), for Pyrogen testing

eCl@ss:
32160606

Agency

EP Chapter 2.6.30

Quality Level

feature

ready-to-use

packaging

pkg of 1 kit

manufacturer/tradename

PyroMAT®

application(s)

pharmaceutical
pyrogen testing

compatibility

configured for PyroMAT®

shipped in

ambient

storage temp.

2-8°C

suitability

pyrogenic bacteria

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This Item
MATFLAGELLINPYR0MATCELLS1.44154
PyroMAT® kit Reagents and Interleukin-6 ELISA kit for Monocyte Activation Test (MAT), for Pyrogen testing

Millipore

PYR0MATKIT

PyroMAT® kit

PyroMAT® cells Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing, pkg of 2 vials

Millipore

PYR0MATCELLS

PyroMAT® cells

PyroDetect Kit Reagents and Interleukin-1ß ELISA kit for Monocyte Activation test (MAT), for Pyrogen testing

Millipore

1.44154

PyroDetect Kit

packaging

pkg of 1 kit

packaging

-

packaging

pkg of 2 vials

packaging

pkg of 1 kit

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroMAT®

manufacturer/tradename

PyroDetect

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

application(s)

pharmaceutical
pyrogen testing

compatibility

configured for PyroMAT®

compatibility

configured for PyroDetect System, configured for PyroMAT® System

compatibility

configured for PyroMAT® System

compatibility

configured for PyroDetect Systems

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

General description

The PYROMAT® System is a ready-to-use, in vitro solution for pyrogen testing, using the Monocyte Activation Test (MAT). It is based on the Mono-Mac-6 cell line and interleukin 6 (IL-6) read-out. The human monocytes that encounter pyrogens from contaminated sample, produce cytokines (IL-6), which can be detected with an enzyme-linked immunosorbent assay (ELISA). The kit contains the reagents needed to prepare the sample, perform the incubation with the monocytic cells, and the reagents needed for the ELISA detection.

Application

The PYROMAT® System is used to ensure the safety of parenteral pharmaceutical products and medical devices.

Features and Benefits

Ready-to-use kit

Components

  • 96-well plate, Endotoxin free water, RMPI culture medium
  • IL-6 ELISA kit and plate

Storage and Stability

2-8°C

Recommended products

To be used with PYROMAT® cells (PYR0MATCELLS), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN) and IL6 control (PYR0MATIL6)

Legal Information

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


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