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01518

Supelco

Ginsenoside Rd

analytical standard

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Synonym(s):
(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, Gypenoside VIII
Empirical Formula (Hill Notation):
C48H82O18
CAS Number:
Molecular Weight:
947.15
EC Number:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)[C@@H]5CC[C@@]34C

InChI

1S/C48H82O18/c1-21(2)15-22(3)17-48(8,66-43-40(60)37(57)34(54)28(19-50)62-43)24-11-13-47(7)23-9-10-30-45(4,5)31(12-14-46(30,6)25(23)16-26(52)32(24)47)64-44-41(38(58)35(55)29(20-51)63-44)65-42-39(59)36(56)33(53)27(18-49)61-42/h15,22-44,49-60H,9-14,16-20H2,1-8H3/t22?,23?,24-,25?,26-,27+,28+,29+,30?,31?,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42-,43-,44-,46+,47+,48-/m0/s1

InChI key

IRBVCFDYIGGFFY-ADSMOORZSA-N

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1 of 4

This Item
PHL8921103000590PHL80462
Ginsenoside Rd analytical standard

Supelco

01518

Ginsenoside Rd

Ginsenoside Rd phyproof® Reference Substance

PHL89211

Ginsenoside Rd

Ginsenoside Re primary reference standard

03000590

Ginsenoside Re

Ginsenoside Ro phyproof® Reference Substance

PHL80462

Ginsenoside Ro

format

neat

format

neat

format

-

format

-

assay

≥95.0% (HPLC)

assay

≥90.0% (HPLC)

assay

-

assay

≥90.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

application(s)

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

General description

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rd is the main active component of ginsenosides, having the ability to inhibit Ca2+ influx through receptors and store-operated Ca2+ channel. From neural stem cells, it is seen to enhance astrocyte differentiation. It also reduces the 3-nitropropionic acid-induced motor impairment and cell loss in stratum. It constitutes to one of the major ingredient in total saponin content from Panax notoginseng.

Application

It was used as reference standard in UPLC/TOF-MS analysis of human plasma to determine Ginsenoside metabolites.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Sigma-Aldrich

SML0184

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00370580

Ginsenoside Rg1

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64139

Ginsenoside Rg3

Ginsenoside Rh2 analytical standard

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73658

Ginsenoside Rh2

Ginsenoside Rg5 analytical standard

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43016

Ginsenoside Rg5

Gypenoside XVII phyproof® Reference Substance

PHL83506

Gypenoside XVII

Ginsenoside Rf primary reference standard

01580590

Ginsenoside Rf

Hengrui Liu et al.
Cancers, 12(1) (2020-01-18)
The divalent cation-selective channel transient receptor potential melastatin 7 (TRPM7) channel was shown to affect the proliferation of some types of cancer cell. However, the function of TRPM7 in the viability of breast cancer cells remains unclear. Here we show
Shi-Yang Li et al.
Apoptosis : an international journal on programmed cell death, 17(2), 113-120 (2011-11-15)
Our previous studies showed that ginsenoside-Rd, a purified component from Panax notoginseng, inhibited cell proliferation and reversed basilar artery remodeling. The aim of this study was to investigate whether ginsenoside- Rd influences H(2)O(2)-induced apoptosis in basilar artery smooth muscle cells
Ruidong Ye et al.
Neurochemistry international, 58(3), 391-398 (2010-12-28)
We previously found that ginsenoside Rd (Rd), one of the main active ingredients in Panax ginseng, attenuates neuronal oxidative damage in vitro induced by hydrogen peroxide and oxygen-glucose deprivation. In this study, we sought to investigate the potential protective effects
Tian Lin et al.
Journal of ethnopharmacology, 142(3), 754-761 (2012-06-12)
Ginseng, the root of Panax ginseng C. A. MEYER (Araliaceae), is reputedly known for its nootropic and anti-aging functions and has been widely used to treat various diseases and enhance health for thousands of years in Asia. Recent studies revealed
Dong Sun et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(3-4), 369-373 (2011-09-09)
Ginsenoside-Rd (GS-Rd) is one of the major active components of Panax ginseng, and was shown to have the protective effects against several insults. However, we still lack some basic knowledge of GS-Rd, including its pharmacokinetic, tissue distribution and excretion in

Articles

HPLC Separation of Ginsenosides from American Ginseng

The HPLC method for ginsenoside separation was optimized using a ginsenoside standard mixture and then applied to a sample of American Ginseng root. The experimental conditions and chromatograms are shown.

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