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105910

Sigma-Aldrich

Salicylic acid

ReagentPlus®, ≥99%

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Synonym(s):
2-Hydroxybenzoic acid
Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

4.8 (vs air)

Quality Level

vapor pressure

1 mmHg ( 114 °C)

product line

ReagentPlus®

Assay

≥99%

bp

211 °C (lit.)
211 °C/20 mmHg

mp

158-161 °C (lit.)

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Gene Information

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This Item
247588S592227301
Salicylic acid ReagentPlus®, ≥99%

Sigma-Aldrich

105910

Salicylic acid

Salicylic acid ACS reagent, ≥99.0%

Sigma-Aldrich

247588

Salicylic acid

Salicylic acid BioXtra, ≥99.0%

Sigma-Aldrich

S5922

Salicylic acid

Salicylic acid meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

Sigma-Aldrich

27301

Salicylic acid

bp

211 °C (lit.), 211 °C/20 mmHg

bp

211 °C (lit.)

bp

211 °C (lit.)

bp

211 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

General description

Salicylic acid is an aromatic phenolic derivative. It can be prepared industrially via the Kolbe-Schmitt reaction. It is used as a chemical intermediate in organic synthesis for the synthesis of various organic compounds.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
Dorothea Ellinger et al.
Plant physiology, 161(3), 1433-1444 (2013-01-22)
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been generally believed that the papillae provide a
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
Loretta Lazzarato et al.
Journal of medicinal chemistry, 51(6), 1894-1903 (2008-02-26)
A new class of products in which the phenol group of salicylic acid is linked to alkanoyl moieties bearing nitrooxy functions has been synthesized and studied for their polyvalent actions. The products were stable in acid and neutral media, while

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