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47673

Sigma-Aldrich

Formaldehyde solution

tested according to Ph. Eur.

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Synonym(s):
Formaldehydi solutio 35 per centum, Formalin
Linear Formula:
HCHO
CAS Number:
Molecular Weight:
30.03
Beilstein:
1209228
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

vapor density

1.03 (vs air)

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

9.0-15.0 % (v/v) methanol as stabilizer

concentration

25-50%

solubility

water: soluble

density

1.09 g/mL at 25 °C (lit.)

suitability

suitable for manufacturing use (Laboratory chemicals)

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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This Item
25254915512F8775
Formaldehyde solution tested according to Ph. Eur.

Sigma-Aldrich

47673

Formaldehyde solution

Formaldehyde solution ACS reagent, 37 wt. % in H2O, contains 10-15% Methanol as stabilizer (to prevent polymerization)

Sigma-Aldrich

252549

Formaldehyde solution

Formaldehyde solution meets analytical specification of USP, ≥34.5 wt. %

Sigma-Aldrich

15512

Formaldehyde solution

Formaldehyde solution for molecular biology, 36.5-38% in H2O

Sigma-Aldrich

F8775

Formaldehyde solution

solubility

water: soluble

solubility

-

solubility

-

solubility

-

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

density

1.09 g/mL at 25 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

agency

USP/NF

agency

-

agency

-

agency

-

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

vapor density

1.03 (vs air)

Application

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Biochem/physiol Actions

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Caution

may become turbid on storage

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

133.0 °F - closed cup

Flash Point(C)

56.11 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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