PHR1134

Thymol

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 2-Isopropyl-5-methylphenol, 5-Methyl-2-(1-methylethyl)phenol, 5-Methyl-2-isopropylphenol, IPMP
• Linear Formula: 2-[(CH₃)₂CH]C₆H₃-5-(CH₃)OH
• CAS Number: 89-83-8
• Molecular Weight: 150.22
• Beilstein/REAXYS Number: 1907135
• EC Number: 201-944-8
• MDL number: MFCD00002309
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823154
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1449008
• vapor pressure: 1 mmHg ( 64 °C)
• API family: thymol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• bp: 232 °C (lit.)
• mp: 48-51 °C (lit.)
• density: 0.965 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(C)c1ccc(C)cc1O
• InChI: 1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3
• InChI key: MGSRCZKZVOBKFT-UHFFFAOYSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Thymol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0147 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H314,H411
• pcodes: P260 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
• wgk_germany: WGK 2
• flash_point_f: closed cup
• flash_point_c: closed cup