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Key Documents

PHR1275

Supelco

Naphthalene

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Naphthalene

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About This Item

Empirical Formula (Hill Notation):
C10H8
CAS Number:
Molecular Weight:
128.17
Beilstein/REAXYS Number:
1421310
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1457083

vapor density

4.4 (vs air)

vapor pressure

0.03 mmHg ( 25 °C)

CofA

current certificate can be downloaded

autoignition temp.

978 °F

expl. lim.

5.9 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

218 °C (lit.)

mp

80-82 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

c1ccc2ccccc2c1

InChI

1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H

InChI key

UFWIBTONFRDIAS-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Naphthalene is produced from fossil fuels such as coal and petroleum. Its commercial applications include, the production of polyvinyl plastics, moth repellents, dyes, leather tanning agents, resins, etc.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0011 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

173.3 °F - closed cup

flash_point_c

78.5 °C - closed cup


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Toxicological Profile for Naphthalene, 1-methylnaphthalene, and 2-methylnaphthalene (2005)
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Journal of toxicology and environmental health. Part B, Critical reviews, 6(2), 161-183 (2003-01-30)
Results of five previously unpublished studies of the genotoxicity of naphthalene are presented and extensively discussed in relation to the large database that exists in the published literature. According to the published literature, naphthalene has not induced gene mutations in
A Buckpitt et al.
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