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PHR1305

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Sodium dodecylbenzenesulfonate

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Dodecylbenzenesulfonic acid sodium salt
Linear Formula:
CH3(CH2)11C6H4SO3Na
CAS Number:
Molecular Weight:
348.48
Beilstein/REAXYS Number:
4171051
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1623637

API family

sodium dodecylbenzenesulfonate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

[Na+].CCCCCCCCCCCCc1ccc(cc1)S([O-])(=O)=O

InChI

1S/C18H30O3S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-17-13-15-18(16-14-17)22(19,20)21;/h13-16H,2-12H2,1H3,(H,19,20,21);/q;+1/p-1

InChI key

JHJUUEHSAZXEEO-UHFFFAOYSA-M

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1 of 4

This Item
289957PHR1231PHR1609
vibrant-m

PHR1305

Sodium dodecylbenzenesulfonate

vibrant-m

289957

Sodium dodecylbenzenesulfonate

vibrant-m

PHR1231

Sodium benzoate

vibrant-m

PHR1609

Sodium Dehydroacetic Acid

format

neat

format

-

format

neat

format

neat

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

technical grade

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-30°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-30°C

agency

traceable to USP 1623637

agency

-

agency

traceable to USP 1055002, traceable to USP 1613564

agency

traceable to USP 1166309

General description

Sodium dodecylbenzenesulfonate, commonly known as sodium lauryl phenyl sulfonate, is a linear alkylbenzene sulfonate that belongs to the class of anionic surfactants. Generally, it is used as an emulsifier, detergent, solubilizer and wetting agent in pharmaceutical, personal care, home care and food products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Sodium dodecylbenzenesulfonate may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, environmental samples, personal care and home care formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3264 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

No data available

flash_point_c

No data available


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Simple and rapid determination of linear alkylbenzene sulfonates by in-tube solid-phase microextraction coupled with liquid chromatography
Hirayama Y, et al.
Journal of Health Science, 52(3), 228-236 (2006)
Determination of surfactant mixtures in shampoos and detergents by HPLC
Nakamura K and Morikawa Y
Journal of the American Oil Chemists' Society, 61(6), 1130-1135 (1984)
Amended safety assessment of dodecylbenzenesulfonate, decylbenzenesulfonate, and tridecylbenzenesulfonate salts as used in cosmetics
Becker LC, et al.
International Journal of Toxicology, 29, 288S-305S (2010)
Development of a method by HPLC to determine LAS and its application in anaerobic reactors
Duarte I, et al.
Journal of the Brazilian Chemical Society, 17(7), 1360-1367 (2006)
Adsorption of linear alkyl benzene sulfonates on oil-water interface: Effects of Na+, Mg2+ and Ca2+ ions
Anachkov SE, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 466, 18-27 (2015)

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