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average Mn ~362

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Brij® L4, Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
Linear Formula:
CAS Number:
MDL number:



Quality Level


semisolid (may be liquid)

mol wt

average Mn ~362

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.


≤1.0% water

refractive index

n20/D 1.451 (lit.)

acid number

≤2.0 mg KOH/g

hydroxyl value

144‑165 mg KOH/g


0.95 g/mL at 25 °C (lit.)



greener alternative category

SMILES string




InChI key


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General description

ECO Brij® L4, also known as polyethylene glycol lauryl ether, is a bio-based, nonionic surfactant manufactured from naturally occurring straight-chain lauryl alcohol. This detergent, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting, making it suitable for a range of applications in biochemical and biological research.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Physical properties

The ECO Brij series of ethoxylated fatty alcohols are non-ionic surfactants manufactured using renewable sources. ECO Brij L4 is a mixture of tetraethylene glycol alkyl ethers, primarily dodecyl (C12) ether. The alkyl ether profile of ECO Brij L4 may differ lot-to-lot due to natural variability in the lipid starting material (palm oil).

Legal Information

Brij is a registered trademark of Croda International PLC
ECO BRIJ is a registered trademark of Croda Inc.


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Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Jun Koizumi et al.
AJR. American journal of roentgenology, 199(1), 200-207 (2012-06-27)
Balloon-occluded retrograde transvenous obliteration has been traditionally based on liquid sclerotherapy. However, overdose and systemic spillage of liquid sclerosant can cause severe complications, such as hemolysis, which lead to hemoglobinuria, allergy, acute respiratory distress syndrome, and other disorders. The purpose
Jacomina W van den Esschert et al.
Annals of surgery, 255(2), 311-318 (2012-01-14)
To compare the safety and hypertrophy response after portal vein embolization (PVE) using 2 absorbable and 3 permanent embolization materials. Portal vein embolization is used to increase future remnant liver volume preoperatively. Application of temporary, absorbable embolization materials could be
Takashi Yamaki et al.
Journal of vascular surgery, 56(6), 1649-1655 (2012-05-23)
This study assessed changes in the calf muscle deoxygenated hemoglobin (HHb) level during light-intensity exercise after ultrasound-guided foam sclerotherapy (UGFS) for superficial venous insufficiency. UGFS with 1% or 3% polidocanol foam (POL-F) was used to treat unilateral great saphenous vein
S Rathbun et al.
Phlebology, 27(3), 105-117 (2012-02-22)
Endovenous foam sclerotherapy (EFS) is used widely throughout the USA for the treatment of venous disorders. The purpose of the quantitative meta-analysis was to systematically and comprehensively evaluate the literature to provide accurate estimates of safety and efficacy outcomes for
B McAree et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 43(6), 721-725 (2012-04-18)
To compare the half-life of STD and polidocanol air-based foams and the damage they inflict upon human great saphenous vein in an in-vitro model. The time for the volume of 3% STD and polidocanol foams to reduce by 10% (T(90))

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