107603

Sodium formate

reagent grade, 97%

• Synonym(s): Formic acid sodium salt
• Linear Formula: HCOONa
• CAS Number: 141-53-7
• Molecular Weight: 68.01
• Beilstein/REAXYS Number: 3595134
• EC Number: 205-488-0
• MDL number: MFCD00013101
• UNSPSC Code: 12352300
• eCl@ss: 39021901
• PubChem Substance ID: 329749126
• NACRES: NA.55

Properties

• grade: reagent grade
• assay: 97%
• form: crystalline powder; powder, crystals or granules
• mp: 259-262 °C (lit.)
• solubility: water: soluble(lit.)
• SMILES string: [Na+].[O-]C=O
• InChI: 1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1
• InChI key: HLBBKKJFGFRGMU-UHFFFAOYSA-M

Description

General description

Sodium formate is the colorless sodium salt of formic acid. It can be prepared by reacting formic acid with sodium hydroxide or carbonate. Its crystal structure has been investigated. Its crystals exhibit monoclinic-holohedral symmetry.

Application

• Engineering Redox Cofactor Balance for Improved 5-Methyltetrahydrofolate Production in Escherichia coli.: Sodium formate was used to manipulate redox cofactor balance, significantly enhancing the production of 5-methyltetrahydrofolate in E. coli, showcasing its potential in metabolic engineering applications (Yang et al., 2024).


• Intensity-dependent mass search for improving metabolite database matches in chemical isotope labeling LC-QTOF-MS-based metabolomics.: Sodium formate was utilized in isotope labeling for LC-QTOF-MS, improving metabolite database matching accuracy, thus enhancing metabolomics data quality (Li et al., 2023).


• High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades.: The study highlights sodium formate′s role in enzymatic cascades for the efficient synthesis of enantiopure amino alcohols, important intermediates in pharmaceutical synthesis (Corrado et al., 2022).


• UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant.: Sodium formate was used as a reference standard in UPLC-ESI-QTOF/MS, providing insights into minimizing experimental artefacts in blood plasma and serum metabolomics (Barri and Dragsted, 2013).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable