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208213

Sigma-Aldrich

Polyphosphoric acid

greener alternative

reagent grade, 115% H3PO4 basis

Linear Formula:
Hn+2PnO3n+1
CAS Number:
EC Number:
MDL number:
eCl@ss:
38070203
NACRES:
NA.21

grade

reagent grade

Quality Level

Assay

115% H3PO4 basis

form

viscous liquid

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

bp

300 °C (lit.)

density

2.06 g/mL at 25 °C

greener alternative category

InChI

1S/O5P2.H3O4P/c1-2-7-4-3-6(1)5-7;1-5(2,3)4/h;(H3,1,2,3,4)

InChI key

FVYIVXLIMHNYTD-UHFFFAOYSA-N

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1 of 4

This Item
8.0747139860830755
Polyphosphoric acid reagent grade, 115% H3PO4 basis

Sigma-Aldrich

208213

Polyphosphoric acid

Polyphosphoric acid for synthesis

Sigma-Aldrich

8.07471

Polyphosphoric acid

Polyphosphoric acid ~105% H3PO4 basis

Sigma-Aldrich

398608

Polyphosphoric acid

Perchloric acid puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 70.0-72.0%

Sigma-Aldrich

30755

Perchloric acid

assay

115% H3PO4 basis

assay

83-87% P2O5 basis (acidimetric)

assay

~105% H3PO4 basis

assay

70.0-72.0%

form

viscous liquid

form

viscous liquid

form

viscous liquid

form

liquid

bp

300 °C (lit.)

bp

530 °C/1013 hPa

bp

300 °C (lit.)

bp

-

density

2.06 g/mL at 25 °C

density

2.06 g/cm3 at 20 °C

density

1.9 g/mL at 25 °C

density

1.670 g/cm3

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

General description

Polyphosphoric acid (PPA) is widely employed as acylation and alkylation reagent in various reactions. It is a strong mineral acid with excellent dehydrating properties.

Application

Polyphosphoric acid may be used in the synthesis of aromatic sulfones, N-substituted amides and 4-aminobenzophenones. It may also be used in dehydration, Fischer-Indole Synthesis, Beckmann Rearrangement and Schmidt Rearrangement reactions. It can be used as a catalyst in the synthesis of various aromatic ketones.
PPA may be used as a catalyst during the synthesis of dimethyl carbonate (DMC) from urea and methanol. It also acts as an absorbent for the ammonia generated in the process. PPA may be used to prepare silica-supported polyphosphoric acid (PPA-SiO2), an easy to handle, reusable heterogenous catalyst.

Other Notes

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1


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Customers Also Viewed

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1 of 3

Silica-supported polyphosphoric acid (PPA-SiO2): An efficient and reusable heterogeneous catalyst for ecofriendly organic synthesis.
Vekariya RH, et al.
Synthetic Communications, 46(3), 197-219 (2016)
906. Synthetic uses of polyphosphoric acid.
Denton DA and Suschitzky H.
Journal of the Chemical Society, 4741-4743 (1963)
D S Robertson
Medical hypotheses, 62(1), 97-111 (2004-01-20)
A hypothesis concerning the mode of formation of the components of DNA and RNA in living cells is described. This is based on the reversible hydration and dehydration of polyphosphoric acids in the cell. It is shown that formation of
Jean-Philippe St-Pierre et al.
Acta biomaterialia, 6(8), 3302-3309 (2010-03-02)
A major challenge to the successful clinical application of bioengineered cartilage remains its integration to surrounding tissues upon implantation. One way to address this consists of generating biphasic constructs composed of articular cartilage formed in vitro on the top surface
K Maekawa et al.
Journal of oral rehabilitation, 36(5), 362-367 (2009-02-13)
This study was conducted to evaluate the effect of polyphosphoric acid (PPA) treatment on bone regeneration around titanium (Ti) implants in vivo. Adsorption of PPA by Ti was achieved by immersing Ti implants (2 mm in diameter, 4 mm in

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