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103R-9

Sigma-Aldrich

CD3 (MRQ-39) Rabbit Monoclonal Antibody

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NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-39, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

pkg of 0.1 mL concentrate (103r-94)
pkg of 0.5 mL concentrate (103R-95)
pkg of 1.0 mL concentrate (103R-96)
pkg of 1.0 mL predilute (103R-97)
pkg of 7.0 mL predilute (103R-98)

manufacturer/tradename

Cell Marque

IVD

for in vitro diagnostic use

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD3E(916)

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This Item
104R-1SAB5500057107M-2
clone

MRQ-39, monoclonal

clone

SP35, monoclonal

clone

SP162, monoclonal

clone

MRQ-56, monoclonal

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

species reactivity

human

species reactivity

human

species reactivity

human (tested)

species reactivity

human

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

affinity isolated antibody

antibody form

culture supernatant

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

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General description

Anti-CD3 has been considered the best all around T-cell marker. This antibody reacts with an antigen present in early thymocytes. The positive staining of this marker may represent a sign of early commitment to the T-Cell lineage.

Quality


IVD

IVD

IVD

RUO

Linkage

CD3 Positive Control Slides, Product No. 103S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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SM Denning, et al.
Leucocyte Typing III, 144-147 (1987)
E A Clark et al.
Immunology today, 10(7), 225-228 (1989-07-01)
During 1987, striking advances were made in defining the receptors and ligands for cell-to-cell adhesion interactions involving leukocytes. In 1988, two major leukocyte differentiation antigens, CD10 (cALLA) and CD45 (LCA, T200), were shown to be enzymes while two other markers
Ulla Axdorph et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 110(5), 379-390 (2002-06-22)
Morphologically, T-cell-rich B-cell lymphoma (TCRB-NHL) may be indistinguishable from Hodgkin's disease (HD). Immunophenotyping may be helpful in the separation of these entities. TCRB-NHL is occasionally misdiagnosed and treated as HD. However, information is limited regarding clinical characteristics and outcome of
Ahmet Dogan et al.
The American journal of surgical pathology, 27(7), 903-911 (2003-06-27)
Occasionally, primary large B-cell lymphomas (LBLs) arising in the spleen present with a micronodular pattern involving the splenic white pulp but sparing the red pulp. Histologically, the nodules contain scattered large B cells in a background of numerous T cells
Kennosuke Karube et al.
The American journal of surgical pathology, 27(10), 1366-1374 (2003-09-26)
We studied the morphologic, immunohistochemical, and clinical characteristics of 158 cases of lymphoblastic lymphoma. Based on immunophenotyping and cell lineage, cases were classified into B-cell type (CD20,CD19 or CD79a+, n = 53), T-cell type (surface CD3+, n = 84), and

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