143M-1
CD43 (MT1) Mouse Monoclonal Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MT1, monoclonal
Application:
IHC (p)
Citations:
5
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
MT1, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (143M-14), vial of 0.5 mL concentrate (143M-15), bottle of 1.0 mL predilute (143M-17), vial of 1.0 mL concentrate (143M-16), bottle of 7.0 mL predilute (143M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotype
IgG1
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
membranous
Gene Information
human ... SPN(6693)
General description
From 70 to 90% of T-cell Lymphomas and from 22 to 37% of B cell Lymphomas are labeled with this antibody. No reactivity has been observed with reactive B cells. So, a B lineage population that co-expresses a T-cell marker is highly likely to be a malignant lymphoma rather than a reactive B cell population. When used in combination with CD45 and L26, effective immunophenotyping of the majority of paraffin-embedded lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors lymphoma.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD43 Positive Control Slides, Product No. 143S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Arber, DA, et al.
Appl. Immunohistochem., 1, 88-96 (1993)
J K Chan et al.
Histopathology, 12(5), 461-480 (1988-05-01)
This review aims to provide a simple guide and quick reference to the terminology and diagnostic applications of leucocyte monoclonal antibodies. The differentiation cluster terminology, where applicable, is used throughout.
K Sheibani et al.
Human pathology, 18(10), 1051-1062 (1987-10-01)
From the study of over 3,000 immunologically well characterized cases, we have developed a systematic approach for the immunohistologic evaluation of lymphoproliferative disorders (LPD). By using a basic screening panel of antibodies on fresh-frozen sections, LPD can be reliably immunophenotyped.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 143M-15 | 0841683124863 |
| 143M-14 | 0841683124856 |
| 143M-17 | 0841683124887 |
| 143M-18 | 0841683124894 |
| 143M-16 | 0841683124870 |