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47729

Sigma-Aldrich

N-Formyl-Met-Leu-Phe

BioXtra, ≥99.0% (TLC)

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Synonym(s):
Chemotactic peptide, N-Formyl-L-methionyl-L-leucyl-L-phenylalanine, fMLF, fMLP (misnomer but widely used)
Empirical Formula (Hill Notation):
C21H31N3O5S
CAS Number:
Molecular Weight:
437.55
Beilstein/REAXYS Number:
2315783
MDL number:
PubChem Substance ID:

product line

BioXtra

Quality Level

assay

≥99.0% (TLC)

form

powder

color

white

solubility

DMF: 50 mg/mL, clear, colorless

application(s)

cell analysis

storage temp.

2-8°C

SMILES string

CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

InChI key

PRQROPMIIGLWRP-BZSNNMDCSA-N

Gene Information

human ... FPR1(2357)

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1 of 4

This Item
F3506P4126338338
N-Formyl-Met-Leu-Phe BioXtra, ≥99.0% (TLC)

47729

N-Formyl-Met-Leu-Phe

Premium Grade
N-Formyl-Met-Leu-Phe ≥97% (HPLC)

F3506

N-Formyl-Met-Leu-Phe

-
Phe-Phe

P4126

Phe-Phe

-
Fmoc-Phe-OH 98%

338338

Fmoc-Phe-OH

-
assay

≥99.0% (TLC)

assay

≥97% (HPLC)

assay

≥98% (TLC)

assay

98%

product line

BioXtra

product line

-

product line

-

product line

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

color

white

color

-

color

white

color

-

solubility

DMF: 50 mg/mL, clear, colorless

solubility

acetic acid: 20 mg/mL, clear, colorless

solubility

-

solubility

-

Amino Acid Sequence

NFor-Met-Leu-Phe

Biochem/physiol Actions

N-Formyl-Met-Leu-Phe is a potent chemotactic peptide and formyl peptide receptor (FPR) agonist that induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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