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A0542

Sigma-Aldrich

Amprolium hydrochloride

Synonym(s):

1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride

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About This Item

Linear Formula:
C14H19N4Cl · HCl
CAS Number:
137-88-2
Molecular Weight:
315.24
Beilstein/REAXYS Number:
4118699
EC Number:
205-307-5
MDL number:
MFCD00078831
UNSPSC Code:
12161900
PubChem Substance ID:
24890432
NACRES:
NA.25

description

cationic

Quality Level

200

assay

≥98.0% (TLC)

form

powder

mol wt

315.24 g/mol

technique(s)

cell culture | mammalian: suitable
microbiological culture: suitable

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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X Wang et al.
Neuroscience, 144(3), 1045-1056 (2006-12-02)
Thiamine (vitamin B1) deficiency (TD) causes region selective neuronal loss in the brain; it has been used to model neurodegeneration that accompanies mild impairment of oxidative metabolism. The mechanisms for TD-induced neurodegeneration remain incompletely elucidated. Inhibition of protein glycosylation, perturbation
Clara Lemos et al.
European journal of pharmacology, 682(1-3), 37-42 (2012-03-06)
The aim of this study was to characterize the intestinal absorption of thiamine, by investigating the hypothesis of an involvement of Organic Cation Transporter (OCT) family members in this process. [(3)H]-T(+) uptake was found to be: 1) time-dependent, 2) Na(+)-
Studies on the Eimeria of goats at Magadu Dairy Farm SUA, Morogoro, Tanzania.
E N Kimbita et al.
Tropical animal health and production, 41(7), 1263-1265 (2009-02-03)
D Bizon-Zygmańska et al.
Neurochemistry international, 59(2), 208-216 (2011-06-16)
Inhibition of pyruvate (PDHC) and ketoglutarate (KDHC) dehydrogenase complexes induced by thiamine pyrophosphate deficits is known cause of disturbances of cholinergic transmission in the brain, yielding clinical symptoms of cognitive, vegetative and motor deficits. However, particular alterations in distribution of
Mohamed M Ghanem et al.
Preventive veterinary medicine, 84(1-2), 161-170 (2008-02-12)
We compared the therapeutic effect of three anticoccidial drugs (toltrazuril, sulphadimidine and amprolium) in buffalo (Bubalus bubalis) calves experimentally infected with Eimeria bovis (E. bovis) and E. zuernii oocysts (3 x 104oocyst/calf). Buffalo calves (1.5-4 month old, 70-kg body weight)
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