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Key Documents

AV31587

Sigma-Aldrich

Anti-DBP (AB1) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-D site of albumin promoter (albumin D-box) binding protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

34 kDa

species reactivity

pig, dog, bovine, rat, sheep, mouse, horse, human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_001343

UniProt accession no.

Q10586

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DBP(1628)

General description

D site of albumin promoter (albumin D-box) binding protein or DBP is a transcription factor that belongs to the PAR bZIP family. DBP is known to interact with promoter sequences in genes such as CYP2A5, CYP2A5 and albumin. Furthemore, Dbp is reportedly involved in the transcription of certain circadian clock genes.
Rabbit Anti-DBP (AB1) antibody recognizes human, mouse, rat, bovine, and canine DBP.

Immunogen

Synthetic peptide directed towards the middle region of human DBP

Application

Rabbit Anti-DBP (AB1) antibody can be used for western blot assays at a dilution of 1.0μg/ml. The antibody can also be used for IHC applications at 4-8μg/ml, using paraffin-embedded tissues.

Biochem/physiol Actions

DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family (Khatib et al., 1994.

Sequence

Synthetic peptide located within the following region: SSPGHAPARAALGTASGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLA

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Markus Stratmann et al.
Molecular cell, 48(2), 277-287 (2012-09-18)
The transcription factors BMAL1 and CLOCK drive the circadian transcription of clock and clock-controlled genes, such as Dbp. To investigate the kinetics of BMAL1 binding to target genes in real time, we generated a cell line harboring tandem arrays of
Ken Hashimoto et al.
iScience, 25(5), 104337-104337 (2022-05-24)
Introduction of fetal cell cycle genes into damaged adult hearts has emerged as a promising strategy for stimulating proliferation and regeneration of postmitotic adult cardiomyocytes. We have recently identified Fam64a as a fetal-specific cell cycle promoter in cardiomyocytes. Here, we

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