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P2906

Sigma-Aldrich

Poly(ethylene glycol)

Hybri-Max™, mol wt 3,000-3,700, waxy solid, BioReagent, suitable for hybridoma

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Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
PubChem Substance ID:
24898372
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

200

grade

Hybri-Max™

sterility

autoclaved

product line

BioReagent

form

waxy solid

mol wt

3,000-3,700

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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This Item
812278118981253
Poly(ethylene glycol) Hybri-Max™, mol wt 3,000-3,700, waxy solid, BioReagent, suitable for hybridoma

Sigma-Aldrich

P2906

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, 3,000

Sigma-Aldrich

81227

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, for molecular biology, 1,000

Sigma-Aldrich

81189

Poly(ethylene glycol)

Poly(ethylene glycol) BioUltra, for molecular biology, 6,000

Sigma-Aldrich

81253

Poly(ethylene glycol)

mol wt

3,000-3,700

mol wt

Mr 2700-3300

mol wt

Mr 950-1050

mol wt

Mr 5000-7000

impurities

endotoxin, tested

impurities

insoluble matter, passes filter test, ≤0.001% peroxides (as H2O2)

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

grade

Hybri-Max™

grade

-

grade

for molecular biology

grade

for molecular biology

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It either exists in the form of a linear or branched structure. It aids in the purification and crystal growth of proteins and nucleic acids. PEG along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials. It permits cell fusion through its interaction with the cell membrane.

Application

Poly(ethylene glycol) has been used in the production of monoclonal antibodies.
Recommended for cell fusion.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

281.5 °F - closed cup

Flash Point(C)

138.6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
Yu S, et al.
Neuroscience journal, 145(2), 539-555 (2007)
Harris JM
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Agathe Dubuisson et al.
Cell death & disease, 10(2), 101-101 (2019-02-06)
Development of therapeutic antibodies in oncology has attracted much interest in the past decades. More than 30 of them have been approved and are being used to treat patients suffering from cancer. Despite encouraging results, and albeit most clinical trials
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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