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P5177

Sigma-Aldrich

Methyl palmitate

≥99% (capillary GC)

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Synonym(s):
n-Hexadecanoic acid methyl ester, Methyl hexadecanoate, Palmitic acid methyl ester
Linear Formula:
CH3(CH2)14CO2CH3
CAS Number:
Molecular Weight:
270.45
Beilstein/REAXYS Number:
1780973
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

plant (palm)

Quality Level

assay

≥99% (capillary GC)

form

solid

refractive index

n20/D 1.4512 (lit.)

bp

185 °C/10 mmHg (lit.)

mp

32-35 °C (lit.)

density

0.852 g/mL at 25 °C (lit.)

functional group

ester

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCCCC(=O)OC

InChI

1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3

InChI key

FLIACVVOZYBSBS-UHFFFAOYSA-N

Gene Information

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1 of 4

This Item
W50953150374PHR3538
vibrant-m

P5177

Methyl palmitate

vibrant-m

W509531

Methyl palmitate

vibrant-m

50374

Methyl palmitate

vibrant-m

PHR3538

Methyl Palmitate

assay

≥99% (capillary GC)

assay

≥97%

assay

-

assay

-

biological source

plant (palm)

biological source

Cocos nucifera, palm oil, synthetic

biological source

-

biological source

-

form

solid

form

-

form

-

form

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-30°C

General description

Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a muscurinic receptors antagonist. Methyl palmitate functions as a vasodilator and relaxes the arterioles in retina upon electrical depolarization. In the superior cervical ganglion, methyl palmitate modulates nicotinic receptor. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. PAME activates Kv7 channels and promotes perivascular adipose tissue.

Application

Methyl palmitate has been used to test impact of cerebral blood flow using laser doppler flowmetry (LDF) experiments and as a standard to determine retention indices (RIs) using gas chromatograph−mass spectrometer

Biochem/physiol Actions

Methyl palmitate has anti-inflammatory and anti-fibrotic effect. Methyl palmitate prevents bleomycin-induced lung inflammation and fibrosis in rats, by inhibiting NF-κB . Methyl palmitate also prevents CCl4-induced liver fibrosis linked to reduced TGF-β .

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113.0 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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USP

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Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion
Lin HW, et al.
Proceedings of the National Academy of Sciences of the USA, 1051(49), 19526-19531 (2008)
Palmitic acid methyl ester and its relation to control of tone of human visceral arteries and rat aortas by perivascular adipose tissue
Wang N, et al.
Frontiers in Physiology, 9 (2018)
Terminal double bonds in the alkenes and acetates of defensive secretion from the thrips Suocerathrips linguis Mound & Marullo, 1994 (Thysanoptera: Phlaeothripidae)
Gehlsen U, et al.
Chemoecology, 19(2), 97-102 (2009)
Jiao Liu et al.
Biotechnology for biofuels, 8, 229-229 (2016-01-01)
Fatty acid composition is an important physiological parameter of microalgae, which is taken as the third generation alternative resource of biodiesel. To boost microalgal research and applications, a convenient, rapid, and acid-catalyzed transesterification procedure that satisfies the demand for the
Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest
Lee RHC, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids (2018)

Articles

Separation of Methyl oleate; Caprylic acid; Heptanoic acid; Methyl decanoate; Methyl dodecanoate; Myristic acid; Methyl palmitate; Methyl palmitoleate; Methyl stearate; Methyl linoleate; Methyl linolenate; Acetic acid; Arachidic acid; Behenic acid; Propionic acid; Isobutyric acid; Valeric acid; Isovaleric acid; Isocaproic acid; Butyric acid

Protocols

Protocol for GC Analysis of Bacterial Acid Methyl Esters (BAMEs) on Equity®-1

Separation of Methyl decanoate; Methyl dodecanoate; Methyl myristate; Methyl palmitate; Methyl caprylate; Methyl oleate; Methyl linoleate; Methyl linolenate; Methyl stearate

-11-eicosenoate; Methyl elaidate; Methyl linoleate; Methyl myristate; Methyl myristoleate; Methyl palmitate; Methyl palmitoleate; Methyl oleate; Methyl pentadecanoate; Methyl tridecanoate; Methyl behenate; Methyl caprylate; Methyl erucate; Methyl heptadecanoate; Methyl arachidate

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