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P6888

Sigma-Aldrich

6-Phosphogluconic acid trisodium salt

≥95% anhydrous basis

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Synonym(s):
D-Gluconate 6-phosphate trisodium salt
Empirical Formula (Hill Notation):
C6H10Na3O10P
CAS Number:
Molecular Weight:
342.08
Beilstein/REAXYS Number:
3814212
EC Number:
MDL number:
PubChem Substance ID:

biological source

synthetic (inorganic)

assay

≥95% anhydrous basis

form

powder

impurities

≤0.2% glucose-6-phosphate

color

light yellow

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 18-21% (anhydrous)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H13O10P.3Na/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);;;/q;3*+1/p-3/t2-,3-,4+,5-;;;/m1.../s1

InChI key

CBQSOSFCUWVWAQ-CXKLNRRHSA-K

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1 of 4

This Item
P7877P8877G6526
solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear to hazy, colorless

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥95% anhydrous basis

assay

≥97% (enzymatic)

assay

≥93% dry basis (enzymatic)

assay

≥95% anhydrous basis (enzymatic)

impurities

≤0.2% glucose-6-phosphate

impurities

<0.05 mol % glucose-6-phosphate

impurities

<14% water (Karl Fischer)

impurities

-

color

light yellow

color

light yellow

color

white

color

white

Application

6-Phosphogluconic acid has been used in a study to assess a new phosphorylated intermediate in glucose oxidation. It has also been used in a study to investigate direct oxidation of flucose-6-phosphate by animal tissues.

Preparation Note

Prepared enzymatically.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Direct oxidation of glucose-6-phosphate by animal tissues.
F DICKENS et al.
Nature, 166(4209), 33-33 (1950-07-01)
Yasaman Barekatain et al.
Communications biology, 3(1), 328-328 (2020-06-27)
Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted 1H spectra of intact biological material and limiting diagnostic utility. Here, we show that
A new phosphorylated intermediate in glucose oxidation.
J MACGEE et al.
The Journal of biological chemistry, 210(2), 617-626 (1954-10-01)

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