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PZ0229

Sigma-Aldrich

PF-03246799 hydrochloride

≥98% (HPLC)

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Synonym(s):
6,7,8,9-Tetrahydro-2-(phenylmethyl)-5H-pyrimido[4,5-d]azepine hydrochloride, PF-3246799 hydrochloride
Empirical Formula (Hill Notation):
C15H17N3 · xHCl
CAS Number:
Molecular Weight:
239.32 (free base basis)
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

room temp

SMILES string

C1(CC2=NC(CCNCC3)=C3C=N2)=CC=CC=C1.Cl

InChI

1S/C15H17N3.ClH/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15;/h1-5,11,16H,6-10H2;1H

InChI key

ICVPRIZGSIUCOE-UHFFFAOYSA-N

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Show Differences

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This Item
PZ0354PZ0351PZ0250
vibrant-m

PZ0229

PF-03246799 hydrochloride

vibrant-m

PZ0354

PF-04363467 hydrochloride

vibrant-m

PZ0351

PF-2545920 hydrochloride

vibrant-m

PZ0250

PF-04859989 hydrochloride

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

solubility

H2O: 20 mg/mL, clear

solubility

H2O: 3 mg/mL, clear (warmed)

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: 20 mg/mL, clear

color

white to beige

color

white to beige

color

white to brown

color

white to beige

Biochem/physiol Actions

PF-3246799 is a potent serotonin 5-HT2C receptor agonist with an EC50 of 4.5 nM and minimal activity at 5-HT2A and 5-HT2B receptors. PF-3246799 had good efficacy in a preclinical canine model of stress urinary incontinence.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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