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RES0113M-A7

SAFC

MES monohydrate

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Synonym(s):
2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate
Linear Formula:
C6H13NO4S · H2O
CAS Number:
145224-94-8
Molecular Weight:
213.25
Beilstein:
6350956
EC Number:
224-632-3
MDL number:
MFCD00149409
NACRES:
NA.21

biological source

synthetic

Quality Level

400

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals, tested

useful pH range

5.5-6.7

pKa (25 °C)

6.1

mp

>300 °C (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

O.OS(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2

InChI key

MIIIXQJBDGSIKL-UHFFFAOYSA-N

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This Item
1.3707469889PHG0003
MES monohydrate

SAFC

RES0113M-A7

MES monohydrate

2-Morpholinoethanesulfonic acid monohydrate (MES) EMPROVE® EXPERT

SAFC

1.37074

2-Morpholinoethanesulfonic acid monohydrate (MES)

MES monohydrate BioUltra, for molecular biology, ≥99.5% (T)

Sigma-Aldrich

69889

MES monohydrate

MES hydrate

SAFC

PHG0003

MES hydrate

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals, tested

impurities

-

impurities

DNases, none detected, Insoluble matter, passes filter test, Phosphatases, none detected, Proteases, none detected, RNases, none detected

impurities

Endotoxin, microbial, and trace metals; tested

mp

>300 °C (lit.)

mp

>300 °C

mp

>300 °C (lit.)

mp

-

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

foreign activity

-

foreign activity

-

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MES is a biological buffer often referred to as a “Good′s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.

MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Packaging

Product is available in the following package sizes:
RES0113M-A701X: 100g container
RES0113M-A703X: 5kg container
RES0113M-A705X: 25kg container
RES0113M-A706X: 50kg container

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Tongtong Ma et al.
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Fungal genetics and biology : FG & B, 81, 73-81 (2015-06-09)
The mechanisms of cold adaptation by fungi remain unknown. This topic is of high interest due to the emergence of white-nose syndrome (WNS), a skin infection of hibernating bats caused by Pseudogymnoascus destructans (Pd). Recent studies indicated that apart from
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