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S1300

Sigma-Aldrich

Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

2 mg/mL, clone FMC46, purified immunoglobulin, buffered aqueous solution

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Synonym(s):
Monoclonal Anti-CD62L, Anti-L-Selectin
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

FMC46, monoclonal

form

buffered aqueous solution

mol wt

antigen 74-95 kDa

species reactivity

human

concentration

2 mg/mL

technique(s)

flow cytometry: suitable
immunohistochemistry (frozen sections): suitable

isotype

IgG2b

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SELL(6402)

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species reactivity

human

species reactivity

human, pig

species reactivity

human

species reactivity

human

Gene Information

human ... SELL(6402)

Gene Information

human ... SELE(6401)

Gene Information

human ... SELL(6402)

Gene Information

human ... SELL(6402)

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

Allophycocyanin conjugate

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

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Specificity

Recognizes the CD62L (L-Selectin, LAM-1, Leu8, TQ1, LECAM-1, LECCAM-1, DREG) surface antigen. The antibody recognizes an epitope localized to the lectin domain. It inhibits "rolling" interactions and significantly reduces the binding of FITC-yeast phosphomannan monoester core polysaccharide to lymphocytes, monocytes and neutrophils.
5th Workshop: Code No. S061

Immunogen

human PHA-activated peripheral blood mononuclear cells.

Target description

CD62L, a glycoprotein and member of the selectin family of adhesion receptors, is constitutively expressed on all classes of leukocytes including lymphocytes, monocytes, and polymorphonuclear cells. It is expressed on myeloid progenitor cells, erythroid precursor cells, and some thymocytes.

Physical form

Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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