S9008
Anti-Staphylococcal Enterotoxin B antibody produced in rabbit
fractionated antiserum, lyophilized powder
Synonym(s):
Rabbit Anti-SEB
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About This Item
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
Staphylococcus aureus
packaging
vial of 2 mL lyophilized antiserum
technique(s)
indirect ELISA: 1:150,000-1:250,000
storage temp.
2-8°C
target post-translational modification
unmodified
General description
Staphylococcal enterotoxin B is a toxic bacterial superantigen. The staphylococcal enterotoxins family have high sequence similarity.
Immunogen
Staphylococcal enterotoxin B from Staphylococcus aureus.
Application
Anti-Staphylococcal Enterotoxin B antibody produced in rabbit has been used:
- to conjugate with hollow gold nanosphere and as a component of lateral flow immunoassay strip
- in antibody sandwich immunoassay
- for coupling with magnetic beads for detection assay
Biochem/physiol Actions
Staphylococcal enterotoxin B (SEB) is a superantigen that binds to class II MHC molecules on antigen presenting cells. It stimulates large populations of T cells resulting in acute toxic shock syndrome. It is resistant to denaturation and causes outbreaks of food poisoning that includes emetic responses, diarrhea and GI inflammation.
Staphylococcal enterotoxin B compromises the immune system by triggering inflammation and cytokine release.
Physical form
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.
Reconstitution
Reconstitute with 2 ml deionized water.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Lily Zhang et al.
Toxins, 5(10), 1859-1871 (2013-10-25)
The functional activity of superantigens is based on capacity of these microbial proteins to bind to both the β-chain of the T cell receptor (TcR) and the major histocompatibility complex (MHC) class II dimer. We have previously shown that a
Electrogenerated indium tin oxide-coated glass surface with photosensitive interfaces: Surface analysis
Konry T, et al.
Biosensors And Bioelectronics, 22(9-10), 2230-2236 (2007)
Antje Heit et al.
The Journal of experimental medicine, 214(7), 2139-2152 (2017-06-24)
Germinal center T follicular helper cells (GCTfh) in lymphatic tissue are critical for B cell differentiation and protective antibody induction, but whether GCTfh establish clonal derivatives as circulating memory T cells is less understood. Here, we used markers expressed on
Staphylococcal enterotoxins
Balaban N and Rasooly A
International Journal of Food Microbiology, 61(1), 1-10 (2000)
Bacterial toxins?Staphylococcal enterotoxin B
Fries BC and Varshney AK
Microbiology spectrum, 1(2) (2013)
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