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SAB1411211

Sigma-Aldrich

Anti-BDH1 antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

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Synonym(s):
BDH, MGC2723, MGC4347, MGC9788, SDR9C1
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 38.2 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BDH1(622)

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This Item
HPA030947HPA058709SAB4200592
antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... BDH1(622)

Gene Information

human ... BDH1(622)

Gene Information

human ... BDH1(622)

Gene Information

human ... IDH1(3417)

species reactivity

human

species reactivity

rat, human

species reactivity

human

species reactivity

mouse, human

technique(s)

western blot: 1 μg/mL

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:500-1:1000

technique(s)

immunofluorescence: 0.25-2 μg/mL

technique(s)

immunoblotting: 1-2 μg/mL using extracts of mouse brain (S1 fraction)., immunoprecipitation (IP): 10 μg using lysates of HepG2 cells., indirect immunofluorescence: 2-4 μg/mL using U-87 glioblastoma cells.

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General description

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. (provided by RefSeq)

Immunogen

BDH1 (NP_004042.1, 1 a.a. ~ 343 a.a) full-length human protein.

Sequence
MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR

Physical form

Solution in phosphate buffered saline, pH 7.4

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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