SAB2105265
Anti-IFI204 antibody produced in rabbit
affinity isolated antibody
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All Photos(2)
Synonym(s):
Anti-Ifi16, Anti-p204
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
69 kDa
species reactivity
mouse, human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IFI16(3428)
mouse ... Ifi204(15951)
Immunogen
Synthetic peptide directed towards the middle region of mouse Ifi204
Biochem/physiol Actions
Ifi204 inhibits the transcription of ribosomal RNA.Ifi204 may inhibit DNA binding by UBTF. Ifi204 inhibits cell growth via TP53/p53 and RB1-dependent and independent pathways.Ifi204 acts as a coactivator of RUNX2 during osteogenesis. Ifi204 may be involved in macrophage differentiation.Ifi204 enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation.
Sequence
Synthetic peptide located within the following region: EAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQARTSTAQAGT
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Mark N Lee et al.
Nature immunology, 14(2), 179-185 (2012-12-25)
The innate immune system senses viral DNA that enters mammalian cells, or in aberrant situations self-DNA, and triggers type I interferon production. Here we present an integrative approach that combines quantitative proteomics, genomics and small molecule perturbations to identify genes
Maolei Gong et al.
Biology of reproduction, 101(4), 733-747 (2019-07-28)
The seminal vesicles can be infected by microorganisms, thereby resulting in vesiculitis and impairment in male fertility. Innate immune responses in seminal vesicles cells to microbial infections, which facilitate vesiculitis, have yet to be investigated. The present study aims to
p204-Mediated innate antiviral responses in mouse adipose cells and their effects on cell functions.
Lili Yu et al.
Immunology and cell biology, 93(2), 147-157 (2014-10-08)
Viruses can infect adipose tissues. However, innate antiviral responses in adipose cells and their effects on adipocyte function have not yet been intensively investigated. In this study, p204-initiated innate antiviral responses in mouse adipose cells were examined. Cytosolic DNA sensor
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