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Anti-GCNT3 (AA 410-422) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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Anti-C2/4GnT, Anti-C2GnT-M, Anti-C2GnT2, Anti-N-Acetylglucosaminyltransferase 3

biological source


Quality Level



antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

species reactivity

rat, human, mouse, canine


indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.


target post-translational modification


Gene Information

human ... GCNT3(9245)

General description

The GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type) gene codes for an enzyme synthesizing the core of mucin protein and is mapped to human chromosome 15q22.2. The enzyme is predominantly expressed in stomach and colon.


Peptide with sequence C-NKFDPKVDDNALQ from the internal region (near C terminus) of the protein sequence according to NP_004742.1.

Biochem/physiol Actions

Gcnt3 (glucosaminyl (N-acetyl) transferase 3, mucin type) is involved in the biosynthesis of core 2, core 4 and blood group I antigen in secreted mucins. Overexpression of GCNT3 gene is observed in human pancreatic cancer and contributes to elevated mucin formation, aggressive tumorigenesis and decreased patient survival. The GCNT3 gene is known to promote cell proliferation and spheroid formation in tumors. Deletion of GCNT3 gene results in loss of core 2 O-glycan in the stomach and colon.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.


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Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids




Not applicable


Not applicable

Certificates of Analysis (COA)

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Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells.
Jun Y, et al.
Digestive Diseases and Sciences, 60(7), 1977?1990-1977?1990 (2015)
Allelic Skewing of DNA Methylation Is Widespread across the Genome.
Leonard C S, et al.
American Journal of Human Genetics, 86(2), 196-212 (2010)
Molecular Pathways: Mucins and Drug Delivery in Cancer.
Chinthalapally V R, et al.
Clinical Cancer Research (2017)
Keratin 1 Plays a Critical Role in Golgi Localization of Core 2 N-Acetylglucosaminyltransferase M via Interaction with Its Cytoplasmic Tail.
Armen P, et al.
The Journal of Biological Chemistry, 290(10), 6256-6269 (2015)

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