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SAB4502433

Sigma-Aldrich

Anti-SPHK2 antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
SK 2, SPK 2, Sphingosine kinase 2
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 69 kDa

species reactivity

rat, human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SPHK2(56848)

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SAB1300017SAB4500834SAB4502069
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

rat, human, mouse

species reactivity

human

species reactivity

human, rat, mouse

species reactivity

human, rat, mouse

UniProt accession no.

Q9NRA0

UniProt accession no.

Q9NRA0

UniProt accession no.

Q14289

UniProt accession no.

Q13177

Gene Information

human ... SPHK2(56848)

Gene Information

human ... SPHK2(56848)

Gene Information

human ... PTK2B(2185)

Gene Information

human ... PAK2(5062)

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General description

Anti-SPHK2 Antibody detects endogenous levels of total SPHK2 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human SPHK2.

Immunogen Range: 580-629

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Klaudia Sztolsztener et al.
International journal of molecular sciences, 22(22) (2021-11-28)
Increased lipid bioavailability in a diet favors lipid accumulation, enhancing hepatic lipotoxicity and contributing to insulin resistance (IR) development. The aim of our study was to examine time-dependent alterations in the intrahepatic content of sphingolipids and insulin signaling pathway in
Gaëlle Dominguez et al.
Acta neuropathologica communications, 6(1), 25-25 (2018-04-05)
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid (Aβ) peptides and hyperphosphorylated tau protein accompanied by neuronal loss. Aβ accumulation has been associated with an impaired sphingosine 1-phosphate (S1P) metabolism. S1P is generated by sphingosine kinases (SphKs), of

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