SAB4502671
Anti-RPL39, N-Terminal antibody produced in rabbit
affinity isolated antibody
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All Photos(2)
Synonym(s):
60S ribosomal protein L39
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 6 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:60000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RPL39(6170)
General description
Ribosomal protein L39 (RPL39), a component of the 60S ribosomal complex. The RPL39 gene is mapped on human chromosome XQ24.
Immunogen
The antiserum was produced against synthesized peptide derived from human RPL39.
Immunogen Range: 1-50
Immunogen Range: 1-50
Biochem/physiol Actions
Ribosomal protein L39 (RPL39) plays a major role in spermatogenesis and translation. It might participate in ribosome biogenesis. Mutations in the RPL39 gene are associated with breast cancer and lung metastasis. RPL39 is capable of disrupting nitric oxide synthase and hypoxia signaling pathway. Overexpression of RPL39 can enhance wound-healing in MDAMB231 and BT549 cells. Antibody detects endogenous levels of total RPL39 protein.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Bhuvanesh Dave et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8838-8843 (2014-05-31)
We previously described a gene signature for breast cancer stem cells (BCSCs) derived from patient biopsies. Selective shRNA knockdown identified ribosomal protein L39 (RPL39) and myeloid leukemia factor 2 (MLF2) as the top candidates that affect BCSC self-renewal. Knockdown of
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