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SAB4700015

Sigma-Aldrich

Monoclonal Anti-B2M-Biotin antibody produced in mouse

clone B2M-02, purified immunoglobulin, buffered aqueous solution

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Synonym(s):
Anti-β-2-microglobulin
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

biotin conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

B2M-02, monoclonal

form

buffered aqueous solution

species reactivity

human, pig

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... B2M(567)

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SAB4700010SAB4700014SAB4700013
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human, pig

species reactivity

human

species reactivity

human, pig

species reactivity

human

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

Gene Information

human ... B2M(567)

Gene Information

human ... B2M(567)

Gene Information

human ... B2M(567)

Gene Information

human ... B2M(567)

clone

B2M-02, monoclonal

clone

B2M-01, monoclonal

clone

B2M-02, monoclonal

clone

B2M-01, monoclonal

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General description

The antibody B2M-02 reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.

Immunogen

Purified isolated human beta2-microglobulin

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:200. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Beate Rieblinger et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(10) (2021-03-05)
Genetically modified animals continue to provide important insights into the molecular basis of health and disease. Research has focused mostly on genetically modified mice, although other species like pigs resemble the human physiology more closely. In addition, cross-species comparisons with

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